Around 121 million people worldwide area affected by depression. People with severe depression may commit suicide, i.e. 8, 50,000 deaths due to suicide every year. The prevalence of depression in patients may be as high as 40% in hospital and nursing home settings and 8%–15% in community settings. High prevalence of sleep problems, fatigue and depression are reported in end-stage renal disease (ESRD) patients. Research approach selected for the present study was descriptive (survey research) and cross sectional design. The sample of the study was newly appointed staff nurses working in K.C.G Hospital, Bangalore.