Hospital waste refers to all waste, biologic or non biologic that is discarded and not for further use in any circumstances. Biomedical waste (BMW) is created in hospitals, research and health care teaching institutes, clinics, laboratories, blood banks, animal homes and veterinary institutes. The objectives of the study are to assess the knowledge level among staff nurses, to find out the association between knowledge level with their socio demographic variables and to develop and distribute an information booklet regarding bio medical waste management. The descriptive design was used to conduct the study with 60 staff nurses selected as convenient sampling technique. The results are the majority of the staff nurses 30(50%) had adequate knowledge and 27(45%) had moderate knowledge, 03(05%) had inadequate knowledge. The association between socio demographic variables like age in years and non significant was gender and religion shows significant