The purpose of this paper is to discuss an approach and actions taken by Malaysian government in facing COVID-19 from the point of view of KESBAN Strategy focus on Malaysian East Coast Economic Region (ECER) as a case studies. This study using qualitative approach by In-depth interviews were conducted with Malaysian Health Ministry (MOH), Malaysian National Security Council (NSC), Malaysian Royal Police (RMP), Malaysian Armed Force (MAF), East Coast Economic Region (ECER), Kelantan, Terengganu and Pahang State Economic Planning Unit and National Special Operations Force (Malaysia) to analyze COVID-19 pandemic and its effect on the socio-economic development & security enforcement in ECER on security and health policy documents and reports in order to investigate the roles and practices of the Malaysian security and development agencies during the COVID-19 pandemics.