The term chemotherapy is a general one used in association with any treatment involving the use of chemical agents to stop cancer cell growth. A number of people fear chemotherapy treatment because they have heard that it may present side effect which are comfortable management of the side effects related to chemotherapy has come a long way over the last few decades’ number of the side effects related to chemotherapy treatment may be either controlled or prevented entirely. The objectives of the study are to assess the level of knowledge, to determine the effectiveness of information booklet on selected side effects of chemotherapy among patients with cancer