Tuberculosis is an infectious disease that primarily affects the lungs parenchyma. It is the second leading cause of death worldwide after HIV-AIDS killing nearly 2 million people each year. The current study aimed to assess the level of knowledge regarding the prevention of TB among relatives of TB patients using a self structured interview schedule.The objective of the study wasto assess the level of knowledge, To find out association between levels of knowledge regarding prevention of TB among relatives of TB patients with their selected demographic variables.