Trace minerals are important elements for the growth and sustainability of the functions of the body’s systems, including the Females Reproductive Tract (FRT). The importance these elements, such as Zinc (Zn), Magnesium (Mg), and Copper (Cu), have structural, protective, and immune roles. Most of them participate in many enzymatic reactions, so they are of crucial importance. During the COVID-19 pandemic. Coronavirus invades the body by binding to the angiotensin-converting enzyme 2 (ACE2) receptors which are expressed in many tissues and organs, such as the FRT. The importance of these minerals was demonstrated through the clear impact of their concentrations within the body in inhibiting or progressing the severity of infection.