This study investigates the role of HRM practices in enhancing employee engagement and retention, incorporating innovative methods such as a mixed-methods approach and advanced data analytics. By integrating quantitative surveys, qualitative interviews, and comprehensive case studies, the research provides a holistic view of effective HRM strategies. New methods, including the use of thematic analysis software and inferential statistical tools, offer deeper insights into the relationship between HRM practices and employee outcomes. Findings reveal that performance management, training and development, recognition programs, and work-life balance initiatives significantly impact engagement and retention. Additionally, strategic recruitment, onboarding, career development, and competitive compensation are essential for reducing turnover. This research underscores the importance of tailored HRM practices in fostering a motivated and committed workforce, ultimately leading to enhanced organizational performance.