Polyvinyl alcohol (PVA) membranes were modified by blending with sodium alginate (SA) and polyethylene glycol (PEG). The membranes exhibited good transparency and dimensional stability for different PEG content. The physical handling of membranes was good. The Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA) were carried out to investigate the thermal stability of membranes. DSC showed reduction in the heat of fusion which may be due to the dilution of the inherent crystallinity of PVA by incorporation of the PEG fraction, The thermal stability of members with different PEG content as measured by TGA was also almost identical in trend. These flexible membranes are excellent materials for the biomedical application in human healthcare.