ISSN: 2265-6294

RENAL PROTECTIVE EFFECT OF PLEUROTUS OSTREATUS AND LENTINUS SUBNUDUS IN STREPTOZOTOCIN- NICOTINAMIDE INDUCED DIABETIC NEPHROPATHY IN RATS

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Sayantan Dutta,Rajesh Nath,Neeraj Jain,Parul Nigam,Shubham Sharma,Princy Verma,Anushka verma,Satyendra Mishra, Kamran Javed Naquvi

Abstract

Diabetic nephropathy is defined clinically as the gradual development of renal impairment in the setting of hyperglycemia. This illness is becoming the leading cause of renal failure in many nations, eventually leading to death. Microalbuminuria (MA) is the most common early sign of diabetic nephropathy (DN), the major cause of chronic kidney disease and endstage renal disease. Diabetic nephropathy development may be slowed by early detection of MA and diabetes therapy. According to the International Diabetic Federation, the prevalence of diabetes in individuals aged 20 to 79 years old was 8.8 percent in 2015, indicating that the illness afflicted nearly 440 million people globally.

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