In the process of playing Liszt’s Études D’exécution transcendante, the performer will encounter various technical difficulties. This set of works provides diversified technical training requirements and plays an unprecedented role in the expansion and innovation of piano technology. This research takes the 11th Etude Harmonies du soir in Études D'exécution transcendante as an example. The research goal is to: 1) To combine analysis of musical technique with analysis of artistic content；2) To understand the content of the work from a diverse perspective; 3) To explore the details of the performance of the work in the context of practice and provide performance guidance.