The Corona pandemic is considered the most critical event in the twenty-first century due to the repercussions that negatively affected the entire global system. However, many countries have adopted the principle of cooperation, especially the major countries, like China which relied on the Facemask Diplomacy and provided medical aid to other countries in need. This pandemic has weakened the international cooperation and the role of many countries and regional blocs after failing to deal with this global crisis. This pandemic will leave traces on the global economic system, which may last for many decades in conjunction with the apparent change in the patterns of relations in the international system