The term adjustment, akin to biological adaptation, embodies the efforts made by individuals to cope with changes in their surroundings. Transitioning into college life introduces myriad novel experiences and stimuli, potentially influencing one's adjustment process. This study delves into the adjustment dynamics among college students in Manipur, with a focus on demographic factors. Employing a descriptive research design and a quantitative approach, data was gathered from 1071 college-going adolescents in Manipur using a two-stage sampling technique. Socio-demographic information was collected through interviews utilizing a self-developed semi-structured proforma, while the Adjustment Inventory for College Students (AICS-SS) was employed as the study tool. The results revealed that overall adjustment predominantly fell within the unsatisfactory category (82%), with only 16% and 2% in the average and good categories, respectively. This trend was consistent across various adjustment domains, including home, health, social, emotional, and educational aspects. Furthermore, the study found that variables such as place of residence and annual family income did not exhibit significant relationships with overall adjustment. These findings underscore the pressing need for timely interventions to address the mental wellbeing of college students in Manipur, given the prevailing challenges in adjustment.