The article sets the task to determine the impact of the production infrastructure on the volume of the gross regional product and industrial output of the Navoi region, as well as the dependence model of the indicators of electricity supply, natural gas, water disposal and freight turnover, which are part of the developed industrial infrastructure, in terms of the volume of the gross regional product and industrial output. The relationship between the factors of the constructed model, the reliability of the parameters of the model and the equation were tested according to various criteria. The dynamics of the structure of the production infrastructure of the region was revealed, the positive aspects of the factors influencing the volume of the gross regional product and industrial output were identified, forecasts were made and relevant scientific conclusions were given.