Thailand has an increasing proportion of digital financial transactions, but the value of digital financial transactions is less than those in ASEAN. In addition, there are problems of the cyber security. The objective of this study was to investigate guidelines to promote digital financial transactions in the industrial sector. Both qualitative and quantitative methods were integrated. The quantitative data were collected with the developed questionnaires from 500 industrial entrepreneurs using digital payment. Descriptive, referential, and multivariate statistics were used to analyze the data. It was found that the guidelines for promoting digital financial transactions in the industrial sector were of 5 components prioritized according to their arithmetic mean as follows: 1) Digital environment ( = 4.32), 2) Digital technology ( = 4.31), 3) Stakeholder Development ( = 4.24), 4) Financial Resources ( = 4.17), and 5) Behavioral Inducing ( = 4.06, respectively. The detailed item found most important in each element was: regularly study the rules, regulations and laws related to digital financial transactions; improve basic digital technology necessary to be ready and easy to operate, such as the Internet, internal network; reward employees who can develop their digital skills continuously to serve as role models for employees in the organization; restructure salaries for digital savvy employees; and inform customers and partners about various digital financial transactions that the organization provided for them, respectively. As for the hypothesis testing, it was found that large businesses and small and medium differently at the statistical significance level of 0.05. The analysis of the developed structural equation model revealed that it passed the assessment criteria and was consistent with the empirical data. The calculated values of probability of chi-square, the relative chi-square, the index of consistency, and the root mean squared error of approximation were 0.089, 1.113, 0.952, and 0.015, respectively.