This study was conducted to investigate the concentration of heavy metals (lead, cadmium and mercury) in tap, well and river water along the Tigris River. Water samples were taken from different regions (Mosul, Salahuddin, Baghdad, Wasit and Misan) to study the concentration of these pollutants in the different regions. Chlorine and alum were used in river and well water to reduce pollution in some heavy metals. Lead concentration in the river, tap and well water of the Mousel governorate were significantly higher (P<0.05) compared with other governorates. The different treatment to the river and well water with Chlorine and Alum showed that concentration of lead from the different governorates were decreased significantly (P<0.05) than untreated water except for river and well water of Wasit governorate. However Cadmium concentration in the river and well water of Baghdad, Mousel and Misan governorate were significantly higher (P<0.05) compared with it concentration in other governorates. After river and well water treated with Chlorine and Alum, results showed that cadmium concentration in Baghdad governorate lowest concentration (P<0.05) of the cadmium compared with its concentration in the river and well water of other governorates.