This research dealt with the presentation of the international standard ISO 17025: 2017, including how to design and prepare the procedures guide according to these requirements, how to register on it, and what are the benefits of obtaining a registration certificate, in order to provide an appropriate theoretical framework that enhances the main research contribution in providing a mechanism for preparing a guide The procedures for the quality management system in accordance with the international standard ISO 17025: 2017 mentioned, helps health institutions, including laboratories, in preparing such guides, and encourages the adoption of the standard as a practical response in the direction of competition that it has become facing in light of the rapid development of the health sector. The study consisted of a number of conclusions that showed the poor knowledge of the Yarmouk Teaching Hospital laboratory administration about the importance of quality and the importance of documenting procedures in the ISO 17025: 2017 standard guide to be a tool used in developing the laboratory and moving towards its global accreditation.