This article summarizes the concept of stability of multistorey megastructures affected by seismic and wind activities occurring on the ground or at a certain height. Multi-story buildings must be constructed to withstand wind loads and seismic forces. A building with discontinuities in stiffness and mass will experience concentration of forces and deformations at the point of discontinuity, which can lead to failure of the bars at the intersection and collapse of the building. Methods for stability analysis of columns, load-bearing walls, coupled and coupled elements, cores and single- and multi-story structures are examined. Buildings and structures with lateral supports that use bracing systems, a shear system, or both, such as a wall, to provide stability to the building are considered stable. There have been so many cases in which the structures failed due to instability which require P-Delta analysis. One of the problems is affected from wind load. The calculation methods are computer assisted using the software, STAAD-Pro/ETAB/SAP2000. Comparisons of results are made between the methodologies, software, and different models with different parameters. The P-Delta Analysis of the walled framed structure is done by use of the software.